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The most serious signs and symptoms associated with Marfan syndrome involve the cardiovascular system: undue fatigue, shortness of breath, heart palpitations, racing heartbeats, or chest pain radiating to the back, shoulder, or arm. Cold arms, hands, and feet can also be linked to MFS because of inadequate circulation.
Pain in the affected area [1] [2] Muscle spasm in the affected area [1] Numbness and tingling in an arm or leg [1] [2] Paleness [1] [2] of the skin of the arm or leg; Muscle weakness of an arm or leg, [1] [2] possibly to the grade of paralysis [2] Later symptoms are closely related to infarction of the tissue supplied by the occluded artery:
Symptoms may worsen over the course of several minutes. [4] Typical angina is aggravated by physical activity or emotional stress and is relieved by rest or nitroglycerin. [4] The pain may radiate to other parts of the body, most commonly the left arm or neck. [7] In some individuals, the pain may be less severe and present as pressure or ...
Left arm pain can happen after an injury or pinched nerve. But in some cases, it could be an early indicator of a heart problem. Here’s what you need to know.
There are five signs and symptoms of acute compartment syndrome. [6] They are known as the "5 Ps": pain, pallor, decreased pulse, paresthesia, and paralysis. [6] Pain and paresthesia are the early symptoms of compartment syndrome. [19] [6] Common symptoms are: Pain: A person may feel pain greater than the exam findings. [6]
Weakness comes on slowly (over months to years) in an asymmetric manner and progresses steadily, leading to severe weakness and wasting of arm and leg muscles. IBM is more common in men than women. [10] Patients may become unable to perform activities of daily living and most require assistive devices within 5 to 10 years of symptom onset.
Symptoms classically affect a leg and typically develop over hours or days, [20] though they can develop suddenly or over a matter of weeks. [21] The legs are primarily affected, with 4–10% of DVT occurring in the arms. [11] Despite the signs and symptoms being highly variable, [5] the typical symptoms are pain, swelling, and redness.
Symptoms may also include intermittent claudication or pain at rest. In late stages, paresthesia is replaced by anesthesia (numbness) due to death of nerve cells. [ 11 ] In severe cases, gangrene can occur suddenly and spread rapidly, [ 12 ] and should be treated within six hours of ischaemia.