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A film coating is a thin polymer-based coat that is typically sprayed onto solid pharmaceutical dosage forms, such as tablets, capsules, pellets or granules.Film coating can impact both its appearance and its pharmacokinetics making it an essential process in making the final drug product.
Coating polymer material coated around core. Deposition of liquid polymer coating around core by polymer adsorbed at the interface formed between core material and vehicle phase. Rigidization of coating: coating material is immiscible in vehicle phase and is made rigid. This is done by thermal, cross-linking, or dissolution techniques.
Pharmaceutical engineering is a branch of engineering focused on discovering, formulating, and manufacturing medication, analytical and quality control processes, and on designing, building, and improving manufacturing sites that produce drugs.
Process analytical technology (PAT) has been defined by the United States Food and Drug Administration (FDA) as a mechanism to design, analyze, and control pharmaceutical manufacturing processes through the measurement of critical process parameters (CPP) which affect the critical quality attributes (CQA).
An enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment. [1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine). [2]
There are two types of coating machines used in the pharmaceutical industry: coating pans and automatic coaters. [14] Coating pans are used mostly to sugar coat pellets. Automatic coaters are used for all kinds of coatings; they can be equipped with a remote control panel, a dehumidifier, and dust collectors.
Polymeric coatings are another area of applied grafting techniques. In the formulation of water-borne paint, latex particles are often surface modified to control particle dispersion and thus coating characteristics such as viscosity , film formation, and environmental stability ( UV exposure and temperature variations).
The continuous manner and the effective drying effect enable the integration of electrospinning into continuous pharmaceutical manufacturing systems. [78] The synthesized liquid drug can be quickly turned into an electrospun solid product processable for tableting and other dosage forms.