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The upper limbs or upper extremities are the forelimbs of an upright-postured tetrapod vertebrate, extending from the scapulae and clavicles down to and including the digits, including all the musculatures and ligaments involved with the shoulder, elbow, wrist and knuckle joints. [1]
The mesoderm cells in the limb bud that come from the lateral plate mesoderm will eventually differentiate into the developing limb's connective tissues, such as cartilage, bone, and tendon. [3] Moreover, the mesoderm cells that come from the somites will eventually differentiate into the myogenic cells of the limb muscles. [3]
Limbs are attached to the torso via girdles, either the pectoral girdle for the forelimbs, or the pelvic girdle for the hindlimbs.In terrestrial tetrapods, the pectoral girdles are more mobile, floating over the rib cage connected only via the clavicles (to the sternum) and numerous muscles; while the pelvic girdles are typically fused together anteriorly via a fibrocartilaginous joint and ...
Cells are specified for each segment in the early limb bud and this population of cells expand out as the limb bud grows. This model is consistent with the following observations. Cell division is seen throughout the limb bud. Cell death occurs within a 200 μm zone subjacent to the AER when it is removed; cell death forecloses some patterning.
A forelimb or front limb is one of the paired articulated appendages attached on the cranial end of a terrestrial tetrapod vertebrate's torso. With reference to quadrupeds, the term foreleg or front leg is often used instead. In bipedal animals with an upright posture (e.g. humans and some other primates), the term upper limb is often used.
This cladistic approach defines "tetrapods" as the nearest common ancestor of all living amphibians (the lissamphibians) and all living amniotes (reptiles, birds, and mammals), along with all of the descendants of that ancestor. In effect, "tetrapod" is a name reserved solely for animals which lie among living tetrapods, so-called crown tetrapods.
Stegocephali was re-established to replace the broad definition of Tetrapoda, resolving the usage of two conflicting definitions in discussions of tetrapod evolution. Stegocephali was coined in 1868 by the American paleontologist Edward Drinker Cope , who used it as a general category of prehistoric amphibians.
Polydactyly in early tetrapod aquatic animals, such as in Acanthostega gunnari (Jarvik 1952), one of an increasing number of genera of stem-tetrapods known from the Upper Devonian, which are providing insights into the appearance of tetrapods and the origin of limbs with digits. It also occurs secondarily in some later tetrapods, such as ...