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Intraperitoneal injection or IP injection is the injection of a substance into the peritoneum (body cavity). It is more often applied to non-human animals than to humans. In general, it is preferred when large amounts of blood replacement fluids are needed or when low blood pressure or other problems prevent the use of a suitable blood vessel for intravenous injection.
The peritoneal cavity is widely used in intraperitoneal injections to administer chemotherapy drugs, [5] [6] and is also utilized in peritoneal dialysis. [7] An increase in capillary pressure in the abdominal organs can cause fluid to leave the interstitial space and enter the peritoneal cavity, resulting in a condition called ascites.
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesothelium supported by a thin layer of connective tissue.
While the cecum is usually intraperitoneal, the ascending colon is retroperitoneal. [2] In herbivores, the cecum stores food material where bacteria are able to break down the cellulose. In humans, the cecum is involved in absorption of salts and electrolytes and lubricates the solid waste that passes into the large intestine. [3]
Intraperitoneal, (infusion or injection into the peritoneum) e.g. peritoneal dialysis. Intrathecal (into the spinal canal) is most commonly used for spinal anesthesia and chemotherapy. Intrauterine. Intravaginal administration, in the vagina. Intravenous (into a vein), e.g. many drugs, total parenteral nutrition.
Pneumoperitoneum is pneumatosis (abnormal presence of air or other gas) in the peritoneal cavity, a potential space within the abdominal cavity.The most common cause is a perforated abdominal organ, generally from a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma.
In human anatomy, the mesentery is an organ that attaches the intestines to the posterior abdominal wall, consisting of a double fold of the peritoneum.It helps (among other functions) in storing fat and allowing blood vessels, lymphatics, and nerves to supply the intestines.
Intraperitoneal parts of the GI tract are covered with serosa. These include most of the stomach, first part of the duodenum, all of the small intestine, caecum and appendix, transverse colon, sigmoid colon and rectum. In these sections of the gut, there is a clear boundary between the gut and the surrounding tissue.