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Intraperitoneal injection or IP injection is the injection of a substance into the peritoneum (body cavity). It is more often applied to non-human animals than to humans. In general, it is preferred when large amounts of blood replacement fluids are needed or when low blood pressure or other problems prevent the use of a suitable blood vessel for intravenous injection.
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesothelium supported by a thin layer of connective tissue.
The peritoneal cavity is widely used in intraperitoneal injections to administer chemotherapy drugs, [5] [6] and is also utilized in peritoneal dialysis. [7] An increase in capillary pressure in the abdominal organs can cause fluid to leave the interstitial space and enter the peritoneal cavity, resulting in a condition called ascites.
Secondarily retroperitoneal, meaning the structures initially were suspended in mesentery and later migrated behind the peritoneum during development [3] the duodenum, except for the proximal first segment, which is intraperitoneal [4] ascending and descending portions of the colon (but not the transverse colon, sigmoid and the cecum)
Intraperitoneal antibiotics are preferred to intravenous as they have a greater effect at the area of infection, unless sepsis is present, in which case intravenous antibiotics are indicated. [17] The peritoneal dialysis catheter may have to be removed if the infection does not resolve with antibiotics, and it is recommended that the PD ...
While the cecum is usually intraperitoneal, the ascending colon is retroperitoneal. [2] In herbivores, the cecum stores food material where bacteria are able to break down the cellulose. In humans, the cecum is involved in absorption of salts and electrolytes and lubricates the solid waste that passes into the large intestine. [3]
Pneumoperitoneum is pneumatosis (abnormal presence of air or other gas) in the peritoneal cavity, a potential space within the abdominal cavity.The most common cause is a perforated abdominal organ, generally from a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma.
Peritoneal carcinomatosis (PC) is intraperitoneal dissemination of any form of cancer that does not originate from the peritoneum itself. PC is most commonly seen in abdominopelvic malignancies. PC is most commonly seen in abdominopelvic malignancies.