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Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.
[1] [2] Probiotics are considered generally safe to consume, but may cause bacteria-host interactions and unwanted side effects in rare cases. [3] [4] [5] There is some evidence that probiotics are beneficial for some conditions, such as helping to ease some symptoms of irritable bowel syndrome (IBS). However, many claimed health benefits, such ...
[2] [3] Perhaps the oldest use of a living medicine is the use of leeches for bloodletting, though living medicines have advanced tremendously since that time. Examples of living medicines include cellular therapeutics (including immunotherapeutics ), phage therapeutics , and bacterial therapeutics , a subset of the latter being probiotics .
These characteristics of tolerance to bile concentrations and pH levels serve to classify ME-3 as a probiotic. [14] Limosilactobacillus fermentum ME-3 has also been found to have the capability to suppress mainly gram-negative bacteria. To a lesser extent, ME-3 has also been observed to be able to suppress enterococci and Staphylococcus aureus ...
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
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