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What’s more, CBD may interact with certain drugs, including epileptic drugs, antidepressants, opioid pain-relievers and THC, as well as common medications like acetaminophen (Tylenol) and alcohol.
Taking CBD together with other medications or substances may trigger additional interactions. CBD may amp up the impact of caffeine, for example, says Tory Spindle, PhD, a cannabis researcher and ...
Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
Little is known about potential drug interactions, but CBD mediates a decrease in clobazam metabolism. [64] Work with human liver microsomes shows that cannabidiol inhibits CYP3A5 and CYP3A4 to some degree. [65]
Acetaminophen (also known as paracetamol, brand name Tylenol) concentrations were found to be increased in murine blood by white and pink grapefruit juice, with the white juice acting faster. [64] "The bioavailability of paracetamol was significantly reduced following multiple GFJ administration" in mice and rats.
Tylenol can be used to treat a few different conditions, such as: mild to moderate pain, fever, headaches, muscle aches, toothaches, backaches, colds, and discomfort from a vaccine, says Walia.
CBD is a very low-affinity CB 1 ligand, that can nevertheless affect CB 1 receptor activity in vivo in an indirect manner, while THCV is a high-affinity CB 1 receptor ligand and potent antagonist in vitro and yet only occasionally produces effects in vivo resulting from CB 1 receptor antagonism.
CBD supplements promise to help reduce stress and anxiety, but they can have negative effects on your mental health medications. CBD supplements promise to help reduce stress and anxiety, but they ...