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In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index, [21] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation. [22]
Many health conditions can cause joint pain as a symptom. ... Age 50 to 64: 29 percent. Age ... A 2019 study found that sustained weight loss of 10 to 20 percent of baseline body weight had ...
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
Medical cannabis can be administered through various methods, including capsules, lozenges, tinctures, dermal patches, oral or dermal sprays, cannabis edibles, and vaporizing or smoking dried buds. Synthetic cannabinoids are available for prescription use in some countries, such as synthetic delta-9-THC and nabilone.
Cannabis can be used by smoking, vaporizing, within food, or as an extract. Cannabis has various mental and physical effects, which include euphoria, altered states of mind and sense of time, difficulty concentrating, impaired short-term memory, impaired body movement (balance and fine psychomotor control), relaxation, and an increase in ...
The amendment would have made recreational marijuana legal for adults over 21, with some restrictions. This article originally appeared on Tallahassee Democrat: Florida amendment on marijuana ...
There is significant variation in medical cannabis laws from state to state, including how it is produced and distributed, how it can be consumed, and what medical conditions it can be used for. [2] The first state to effectively legalize medical cannabis was California in 1996, when voters approved Proposition 215 by a 56–44 margin.
Sativex has been approved in 25 countries; clinical trials are underway in the United States to gain FDA approval. [56] In 2007, it was approved for treatment of cancer pain. [54] In Phase III trials, the most common adverse effects were dizziness, drowsiness and disorientation; 12% of subjects stopped taking the drug because of the side ...
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