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  2. Glutathione peroxidase - Wikipedia

    en.wikipedia.org/wiki/Glutathione_peroxidase

    Glutathione peroxidase (GPx) (EC 1.11.1.9) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. [2] The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to ...

  3. Chelation therapy - Wikipedia

    en.wikipedia.org/wiki/Chelation_therapy

    Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...

  4. Cystine/glutamate transporter - Wikipedia

    en.wikipedia.org/wiki/Cystine/glutamate_transporter

    26570 Ensembl ENSG00000151012 ENSMUSG00000027737 UniProt Q9UPY5 Q9WTR6 RefSeq (mRNA) NM_014331 NM_011990 RefSeq (protein) NP_055146 NP_036120 Location (UCSC) Chr 4: 138.16 – 138.24 Mb Chr 3: 49.85 – 50.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cystine/glutamate transporter is an antiporter that in humans is encoded by the SLC7A11 gene. The SLC7A11 gene encodes a sodium ...

  5. Glutathione reductase - Wikipedia

    en.wikipedia.org/wiki/Glutathione_reductase

    Glutathione reductase (GR) also known as glutathione-disulfide reductase (GSR) is an enzyme that in humans is encoded by the GSR gene.Glutathione reductase (EC 1.8.1.7) catalyzes the reduction of glutathione disulfide to the sulfhydryl form glutathione (), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell.

  6. Glutathione S-transferase - Wikipedia

    en.wikipedia.org/wiki/Glutathione_S-transferase

    The MAPEG superfamily of microsomal GSTs consists of subgroups designated I-IV, between which amino acid sequences share less than 20% identity. Human cytosolic GSTs belong to the alpha, zeta, theta, mu, pi, sigma, and omega classes, while six isozymes belonging to classes I, II, and IV of the MAPEG superfamily are known to exist. [8] [12] [13]

  7. Glutathione synthetase - Wikipedia

    en.wikipedia.org/wiki/Glutathione_synthetase

    Glutathione synthetase (GSS) (EC 6.3.2.3) is the second enzyme in the glutathione (GSH) biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine, to form glutathione. [2] Glutathione synthetase is also a potent antioxidant. It is found in many species including bacteria, yeast, mammals, and plants. [3]

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