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An osteocyte, an oblate shaped type of bone cell with dendritic processes, is the most commonly found cell in mature bone. It can live as long as the organism itself. [1] The adult human body has about 42 billion of them. [2] Osteocytes do not divide and have an average half life of 25 years.
Osteocytes do not entirely fill up the canaliculi. The remaining space is known as the periosteocytic space , which is filled with periosteocytic fluid. This fluid contains substances too large to be transported through the gap junctions that connect the osteocytes.
Bone (Osteoblast → Osteocyte) Cartilage (Chondroblast → Chondrocyte) Myofibroblast. Fat Lipoblast → Adipocyte; Muscle Myoblast → Myocyte; Myosatellite cell;
In an ordinary microscopic section, viewed by transmitted light, they appear as fusiform opaque spots. Each lacuna is occupied during life by a branched cell, termed an osteocyte, bone-cell or bone-corpuscle. Lacunae are connected to one another by small canals called canaliculi. A lacuna never contains more than one osteocyte.
Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
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The spaces the cell body of osteocytes occupy within the mineralized collagen type I matrix are known as lacunae, while the osteocyte cell processes occupy channels called canaliculi. The many processes of osteocytes reach out to meet osteoblasts, osteoclasts, bone lining cells, and other osteocytes probably for the purposes of communication ...
Human bones are densely vascularized as in many other mammals. Even though some authors tried to identify a correlation between endothermy and secondary Haversian reconstruction, this feature is absent in many living mammals (e.g. monotremes, Talpa, flying foxes, Herpestes, Dasypus) and birds (Aratinga, Morococcyx, Nyctidromus, Momotus, Chloroceryle) while others possess only scattered ...