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It encodes expected outcomes, both positive and negative, and signals when the expected outcomes do not occur. The mPFC, mediated by the amygdala, is also involved in the extinction and modulation of conditioned responses, including emotional ones, and the augmentation of emotional states.
The ideas of differences between the male and female brains have circulated since the time of Ancient Greek philosophers around 850 BC. In 1854, German anatomist Emil Huschke discovered a size difference in the frontal lobe, where male frontal lobes are 1% larger than those of females. [6]
The ventromedial prefrontal cortex (vmPFC) is a part of the prefrontal cortex in the mammalian brain.The ventral medial prefrontal is located in the frontal lobe at the bottom of the cerebral hemispheres and is implicated in the processing of risk and fear, as it is critical in the regulation of amygdala activity in humans. [2]
[1] Its various components support a variety of functions including emotion, behavior, long-term memory, and olfaction. [2] The limbic system is involved in lower order emotional processing of input from sensory systems and consists of the amygdala, mammillary bodies, stria medullaris, central gray and dorsal and ventral nuclei of Gudden. [3]
People with left inferior frontal lobe damage produced less facial expression and could not analyze emotional situations as well as those with right frontal lobe damage especially with fear and disgust. [n 9] The left inferior frontal gyrus (IFG) plays an important role in anger while the right IFG plays a larger role in disgust. [14]
Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.
The uncinate fasciculus is a bi-directional pathway between the temporal lobe and frontal lobe; it is traditionally considered to be part of the limbic system. [2] It has been proposed that the uncinate fasciculus allows mnemonic representations stored in the temporal lobe to interact with and guide decision making in the frontal lobe. [4]
In human anatomy, the piriform cortex has been described as consisting of the cortical amygdala, uncus, and anterior parahippocampal gyrus. [1] More specifically, the human piriform cortex is located between the insula and the temporal lobe, anteriorly and laterally of the amygdala. [2] [3]