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Pure choriocarcinoma of the testis represents the most aggressive pathologic variant of germ cell tumors in adults, characteristically with early hematogenous and lymphatic metastatic spread. Because of early spread and inherent resistance to anticancer drugs, patients have poor prognosis.
Although choriocarcinoma is a highly malignant tumour and a life-threatening disease, it is very sensitive to chemotherapy. Virtually all women with non-metastatic disease are cured and retain their fertility; the prognosis is also very good for those with metastatic (spreading) cancer, in the early stages, but fertility may be lost.
Unusual names have caused issues for scientists explaining genetic diseases to lay-people, such as when an individual is affected by a gene with an offensive or insensitive name. [13] This has particularly been noted in patients with a defect in the sonic hedgehog gene pathway and the disease formerly named CATCH22 for "cardiac anomaly, T-cell ...
Gestational choriocarcinoma is a form of gestational trophoblastic neoplasia, which is a type of gestational trophoblastic disease (GTD), that can occur during pregnancy. It is a rare disease where the trophoblast , a layer of cells surrounding the blastocyst , undergoes abnormal developments, leading to trophoblastic tumors .
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
For example, the most common cancer of the liver parenchyma ("hepato-" = liver), arising from malignant epithelial cells ("carcinoma"), would be called a hepatocarcinoma, while a malignancy arising from primitive liver precursor cells is called a hepatoblastoma. Similarly, a cancer arising from malignant fat cells would be termed a liposarcoma.
In biology, a pathogen (Greek: πάθος, pathos "suffering", "passion" and -γενής, -genēs "producer of"), in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. [1] The term pathogen came into use in the 1880s.
A human pathogen is a pathogen (microbe or microorganism such as a virus, bacterium, prion, or fungus) that causes disease in humans. The human physiological defense against common pathogens (such as Pneumocystis ) is mainly the responsibility of the immune system with help by some of the body's normal microbiota .