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Pierre Robin sequence [a] (/ p j ɛər r ɔː ˈ b æ̃ /; [3] abbreviated PRS) is a congenital defect observed in humans which is characterized by facial abnormalities.The three main features are micrognathia (abnormally small mandible), which causes glossoptosis (downwardly displaced or retracted tongue), which in turn causes breathing problems due to obstruction of the upper airway.
Petechia of the lower leg in a person with platelets of 3 due to ITP (immune thrombocytopenia).The most common cause of petechiae is through physical trauma such as a hard bout of coughing, holding breath, vomiting, or crying, which can result in facial petechiae, especially around the eyes.
Palatal petechiae. Petechiae on the soft palate are mainly associated with streptococcal pharyngitis , [ 6 ] and as such it is an uncommon but highly specific finding. [ 7 ] 10 to 30 percent of palatal petechiae cases are estimated to be caused by suction, which can be habitual or secondary to fellatio .
Black heel and palm (black heel, calcaneal petechiae, chromidrose plantaire, post-traumatic punctate intraepidermal hemorrhage, tache noir) Callus (callosity, clavus, corn, heloma, heloma durum, heloma molle, intractable plantar keratosis, tyloma) Carbon stain Chilblains; Chilblains (pernio, perniosis)
Submucous cleft palate can also occur, which is a cleft of the soft palate with a split uvula, a furrow along the midline of the soft palate, and a notch in the back margin of the hard palate. [12] The diagnosis of submucous cleft palate often occurs late in children as a result of the nature of the cleft. [ 13 ]
All three disorders cause abnormal brain function or intellectual disability. Hepatosplenomegaly is the enlargement of the liver and spleen which causes digestive problems. [64] It can also cause some kernicterus and petechiae. Kernicterus causes yellow pigmentation of the skin, brain damage, and deafness. [65]
In about 50% of cases, small reddish-purple spots called petechiae can be seen on the roof of the mouth. [26] Palatal enanthem can also occur, but is relatively uncommon. [16] A small minority of people spontaneously present a rash, usually on the arms or trunk, which can be macular (morbilliform) or papular. [16]
It may cause non-fusion of the hard palate, causing cleft palate. It is one of the features of Pierre Robin sequence and Down syndrome. [1] References