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Abnormal dreams; Aggression; Anaphylactic shock; Angioedema (indicative of a hypersensitivity reaction); Arthralgia; Ataxia; Blood glucose disturbances; Bronchospasm (indicative of a hypersensitivity reaction)
The evidence overall supports the effectiveness of bupropion over placebo for the treatment of depression. [41] [18] [42] Some peer-reviewed studies suggest the quality of evidence is low. [42] [18] Some meta-analyses report that bupropion has an at-most small effect size for depression. [43] [44] [42] [45] One meta-analysis reported a large ...
The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is catabolized by monoamine oxidase A in the presence of oxygen , so if care is taken to prevent an unsafe spike in body temperature or metabolic acidosis, oxygenation will assist in dispatching the excess serotonin.
Wellbutrin and other antidepressants may cause an increase in risk of suicide in young adults. If you start to feel suicidal after using Wellbutrin, it’s important to seek professional medical ...
In rare instances, bupropion can increase your risk for seizures. If you have a history of seizures, be sure to mention it to your healthcare professional. Viktoria Korobova/istockphoto
Seizures; Slurred speech; Extrapyramidal symptoms including dyskinesias (acute & delayed) Dystonic reactions; Cogwheel rigidity; Emotional lability; Psychosis; Suicidal ideation; Ataxias; Transient difficulty with recall; Serotonin syndrome; Parkinsonism; Restless leg syndrome; Restlessness; Eye pain; Altered sense of smell; Photophobia ...
The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...
Bupropion has been known to cause seizures in high therapeutic doses and in acute overdoses. For example a 16 year old ingested 1.5 g and developed seizures and cardiotoxicity. [77] There are retrospective case series with good information on dose effect relationships [78] [79] which could be used in the article.