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Methemoglobinemia can be due to certain medications, chemicals, or food or it can be inherited. [2] Substances involved may include benzocaine , nitrites , or dapsone . [ 3 ] The underlying mechanism involves some of the iron in hemoglobin being converted from the ferrous [Fe 2+ ] to the ferric [Fe 3+ ] form. [ 3 ]
Skin conditions in dogs are very common, so it's important to recognize the symptoms and understand the factors that cause them. Dr. Rebecca MacMillan, a vet with over 15 years of experience, says ...
Many dog owners have already heard about the FDA warning and seen the articles on the terrible side effects experienced by some dogs that have been injected with the new arthritis drug Librela ...
Acetaminophen (paracetamol, Tylenol) can cause liver damage in dogs. The toxic dose is 150 mg/kg. [174] Ibuprofen * can cause gastrointestinal irritation, stomach ulcers, and kidney damage in dogs. [175] Naproxen (Aleve)* has a long half-life in dogs and can cause gastrointestinal irritation, anemia, melena (digested blood in feces), and vomiting.
Only special multi-wavelength oximeters (CO-oximeters) can detect methemoglobinemia directly. When there is a "saturation gap" between a low ordinary pulse oximeter reading and a high arterial blood gas analysis result, methemoglobinemia may be suspected.
The structure of cytochrome b5 reductase, the enzyme that converts methemoglobin to hemoglobin. [1]Methemoglobin (British: methaemoglobin, shortened MetHb) (pronounced "met-hemoglobin") is a hemoglobin in the form of metalloprotein, in which the iron in the heme group is in the Fe 3+ state, not the Fe 2+ of normal hemoglobin.
Dogs get ample correct nutrition from their natural, normal diet; wild and feral dogs can usually get all the nutrients needed from a diet of whole prey and raw meat. In addition, a human diet is not ideal for a dog: the concept of a "balanced" diet for a facultative carnivore like a dog is not the same as in an omnivorous human.
Most dogs, however, will need radiation, chemotherapy, and other medications. Even with those therapies, the survival time is short, so ivermectin could help if it proves to be useful.