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The yeast genome is highly accessible to manipulation, hence it is an excellent model for genome engineering. The international Synthetic Yeast Genome Project (Sc2.0 or Saccharomyces cerevisiae version 2.0 ) aims to build an entirely designer, customizable, synthetic S. cerevisiae genome from scratch that is more stable than the wild type.
PomBase is a model organism database that provides online access to the fission yeast Schizosaccharomyces pombe genome sequence and annotated features, together with a wide range of manually curated functional gene-specific data.
In the peer-reviewed literature report, experimental results on function and interaction of yeast genes are extracted by high-quality manual curation and integrated within a well-developed database. The data are combined with quality high-throughput results and posted on Locus Summary pages which is a powerful query engine and rich genome browser.
Saccharomyces cerevisiae was the first eukaryotic organism to have its complete genome sequence determined.. This list of "sequenced" eukaryotic genomes contains all the eukaryotes known to have publicly available complete nuclear and organelle genome sequences that have been sequenced, assembled, annotated and published; draft genomes are not included, nor are organelle-only sequences.
The genome sequence and gene annotation can be browsed through the ORCAE system. The complete genomic data allows scientists to identify homologous proteins and evolutionary relationships between other yeast species and Komagataella. In addition, all seven species were sequenced by 2022. [7]
The second yeast species to have its genome sequenced was Schizosaccharomyces pombe, which was completed in 2002. [108] [109] It was the sixth eukaryotic genome sequenced and consists of 13.8 million base pairs. As of 2014, over 50 yeast species have had their genomes sequenced and published.
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Stentor coeruleus, used in molecular biology (its genome has been sequenced), [5] and is studied as a model of single-cell regeneration.; Dictyostelium discoideum, used in molecular biology and genetics (its genome has been sequenced), and is studied as an example of cell communication, differentiation, and programmed cell death.