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The conjugates of benzoic acid (hippuric acid and the glucuronide of benzoic acid) are rapidly eliminated in urine. [1] When given in large doses to laboratory animals, benzyl benzoate can cause hyperexcitation, loss of coordination, ataxia, convulsions, and respiratory paralysis. [10] Benzyl benzoate can be a skin irritant when used as a ...
Benzoic acid and its salts are used as food preservatives, represented by the E numbers E210, E211, E212, and E213. Benzoic acid inhibits the growth of mold, yeast [23] and some bacteria. It is either added directly or created from reactions with its sodium, potassium, or calcium salt. The mechanism starts with the absorption of benzoic acid ...
Arrow pushing mechanism showing the degradation of a parent paraben into PHBA through base-catalyzed hydrolysis of the ester bond. Another significant paraben degradation product is 4-hydroxybenzoic acid (PHBA). There are two mechanisms in which parabens can degrade to PHBA. The first degradation route occurs chemically.
Personal care products such as hand sanitizers, wet wipes, shampoos, soaps, [4] deodorants and cosmetics. [5] Skin antiseptics and wound wash sprays, such as Bactine. [6] [7] Throat lozenges [8] and mouthwashes, as a biocide; Spermicidal creams. Cleaners for floor and hard surfaces as a disinfectant, such as Lysol and Dettol antibacterial spray ...
The exact mechanism of how parabens work is unknown but they are proposed to act by inhibiting DNA and RNA synthesis, and enzymes like ATPase and phosphotransferase in some bacterial species. It has also been suggested that they interfere with membrane transport processes by disrupting the lipid bilayer and possibly causing the leakage of ...
Compound Benzoin Tincture is often applied to skin under an adhesive bandage. It protects the skin from allergy to the adhesive and makes the bandage adhere longer. [5] It is also used by athletes for its reputation of toughening skin. Orthopedists often apply it under a cast, because it protects the skin and diminishes itching.
Whitfield's ointment is not advised for areas of thinner skin, such as the scrotum or the groin, and in such sites should only be used diluted to half-strength. [ 5 ] A systematic review of the medical literature comparing treatments for ringworm and jock itch was generally critical of the quality of data available.
Toxic effects of retinoids occur with both acute or prolonged intake, depending on which retinoid is considered. The specific toxicity is related to the mechanism of action as well as exposure. A medical sign of chronic or acute poisoning with retinol is hypervitaminosis A, which includes the presence of painful tender swellings on the long bones.
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