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Methylphenidate, sold under the brand names Ritalin (/ ˈ r ɪ t ə l ɪ n / RIT-ə-lin) and Concerta (/ k ə n ˈ s ɜːr t ə / kən-SUR-tə) [citation needed] among others, is a central nervous system (CNS) stimulant indicated in the pharmacotherapy of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
A 2018 Cochrane review found that methylphenidate might be associated with serious side effects such as heart problems, psychosis, and death. The certainty of the evidence was stated as very low. [31] The same review found tentative evidence that it may cause both serious and non-serious adverse effects in children. [31] [a]
[26] [27] [28] Chronic abuse of methylphenidate has the potential to lead to psychosis. [ 29 ] [ 30 ] Similar psychiatric side effects have been reported in a study of ethylphenidate . [ 31 ] No studies regarding psychosis and 4F-MPH or isopropylphenidate have been conducted, but given their high DAT binding and cellular uptake activity, [ 32 ...
The desired effects of steroid precursors however, are often not seen as they do not bind well to androgen receptors. [46] Examples of prohormones include norandrostendione, androstenediol, and dehydroepiandrosterone (DHEA). [45] These steroids have little desired effect compared to anabolic steroids, but have the same side effects. [47]
Most of the adverse effects of Wellbutrin are mild and transient, although a small percentage of people who use this medication experience more severe or longer-lasting side effects. Common side ...
threo-4-Methylmethylphenidate (4-MeTMP) is a stimulant drug related to methylphenidate.It is slightly less potent than methylphenidate and has relatively low efficacy at blocking dopamine reuptake despite its high binding affinity, which led to its investigation as a possible substitute drug for treatment of stimulant abuse (cf. nocaine). [1]
A Michigan judge sentenced the former executive of a specialty pharmacy to at least 10 years in prison Friday for the deaths of 11 people who were injected with tainted pain medication, part of a ...
The long-term effects on mental health disorders in later life of chronic use of methylphenidate is unknown. [204] A 2009 FDA review of 49 clinical trials found that approximately 1.5% of children in clinical trials of medications for ADHD had experienced signs or symptoms of psychosis or mania.