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  2. Doxylamine - Wikipedia

    en.wikipedia.org/wiki/Doxylamine

    Doxylamine is generally safe for administration to healthy adults. Doses of doxylamine of up to 1,600 mg/day for 6 months have been given to adults with schizophrenia, with little toxicity encountered. [33] The median lethal dose (LD 50) is estimated to be 50–500 mg/kg in humans. [34]

  3. Recreational use of dextromethorphan - Wikipedia

    en.wikipedia.org/wiki/Recreational_use_of_dext...

    In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users. A single case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. [17]

  4. Dextromethorphan - Wikipedia

    en.wikipedia.org/wiki/Dextromethorphan

    The average dose necessary for effective antitussive therapy is between 10 and 45 mg, depending on the individual. The International Society for the Study of Cough recommends "an adequate first dose of medication is 60 mg in the adult and repeat dosing should be infrequent rather than qds recommended." [39]

  5. Dextromethorphan regulation by U.S. jurisdiction - Wikipedia

    en.wikipedia.org/wiki/Dextromethorphan...

    A person is prohibited to purchase more than 3.6 grams of dextromethorphan containing products within a 30-day period unless it is in pursuant to a valid prescription. Any person found in violation of this bill is guilty of a misdemeanor and subject to a fine of $1000, or imprisonment of not more than one year, or both the fine and the ...

  6. Dextromethorphan/bupropion - Wikipedia

    en.wikipedia.org/wiki/Dextromethorphan/bupropion

    In Study 1 (GEMINI), a 6-week randomized controlled trial of dextromethorphan/bupropion versus placebo in people with major depressive disorder, scores on the Montgomery–Åsberg Depression Rating Scale (MADRS)—a scale with a range of 0 to 60 points—decreased with dextromethorphan/bupropion by 15.9 points from a baseline score of 33.6 ...

  7. Coricidin - Wikipedia

    en.wikipedia.org/wiki/Coricidin

    Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine). [1] Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer.

  8. Dosage form - Wikipedia

    en.wikipedia.org/wiki/Dosage_form

    The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...

  9. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    Chart of drug dependence potential and relationship between use and lethal dose [33] Chart of relative harmfulness of some psychoactive substances [32] Drug harmfulness is defined as the degree to which a psychoactive drug has the potential to cause harm to the user and is measured in several ways, such as by addictiveness and the potential for ...

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