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The International Agency for Research on Cancer (IARC) rendered PCBs as definite carcinogens in humans. According to the U.S. Environmental Protection Agency (EPA), PCBs cause cancer in animals and are probable human carcinogens. [4] Moreover, because of their use as a coolant in electric transformers, PCBs still persist in built environments ...
Exposure to the coplanar stereoisomer 3,3',4,4',5,5'-hexabromobiphenyl (but not the non-coplanar stereoisomer) in genetically susceptible mice is known to cause immunotoxicity and disorders related to the central nervous system, and even at doses as low as 2.5 mg/kg, excess neonatal fatalities are observed (LD 50 is from 5–10 mg/kg). [1]
The toxicological interactions of PCBs are affected by the number and position of the chlorine atoms, without ortho substitution are referred as coplanar and all others as non-coplanar. [5] Non-coplanar PCBs may cause neurotoxicity by interfering with intracellular signal transduction dependent on calcium. [7]
The World Health Organization has identified glyphosate as "possibly carcinogenic to humans" and a study published earlier this year showed that glyphosate raised the cancer risk of those exposed ...
Oct. 5, 2023: NC State contacted the North Carolina Department of Health and Human Services “regarding concerns about breast cancer cases in people who spent time in Poe Hall,” NCDHHS ...
IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as [1] This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.
In 1994, the US EPA reported that dioxins are a probable carcinogen, but noted that non-cancer effects (reproduction and sexual development, immune system) may pose a greater threat to human health. TCDD , the most toxic of the dibenzodioxins, is classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC).
The agrochemical giant Monsanto has agreed to pay Washington state $95 million to settle a lawsuit that blamed it for pervasive pollution from PCBs — toxic industrial chemicals that have ...