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The blood–ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium. [1] It is a physical barrier between the local blood vessels and most parts of the eye itself, and stops many substances including drugs from traveling across it. [2]
The sclera's blood vessels are mainly on the surface. Along with the vessels of the conjunctiva (which is a thin layer covering the sclera), those in the episclera render the inflamed eye bright red. [6] In many vertebrates, the sclera is reinforced with plates of cartilage or bone, together forming a circular structure called the sclerotic ring.
The episclera is the outermost layer of the sclera (the white of the eye). [1] It is composed of loose, fibrous, elastic tissue and attaches to Tenon's capsule. [1]A vascular plexus is found between the bulbar conjunctiva and the sclera consisting of two layers of vessels, the superficial episcleral vessels and the deep episcleral vessels.
The innermost is the retina, which gets its oxygenation from the blood vessels of the choroid (posteriorly) as well as the retinal vessels (anteriorly). The spaces of the eye are filled with the aqueous humour anteriorly, between the cornea and lens, and the vitreous body , a jelly-like substance, behind the lens, filling the entire posterior ...
The blood retinal barrier has two components: the retinal vascular endothelium and the retinal pigment epithelium. [2] Retinal blood vessels that are similar to cerebral blood vessels maintain the inner blood-ocular barrier. This physiological barrier comprises a single layer of non-fenestrated endothelial cells, which have tight junctions.
The uvea (/ ˈ j uː v i ə /; [1] derived from Latin: uva meaning "grape"), also called the uveal layer, uveal coat, uveal tract, vascular tunic or vascular layer, is the pigmented middle layer of the three concentric layers that make up an eye, precisely between the inner retina and the outer fibrous layer composed of the sclera and cornea.
The optical mechanisms by which the nonpigmented stromal components influence eye color are complex, and many erroneous statements exist in the literature. Simple selective absorption and reflection by biological molecules (hemoglobin in the blood vessels, collagen in the vessel and stroma) is the most important element.
The anterior ciliary arteries contribute arterial blood supply to the rectus muscles, conjunctiva, sclera, [2] [1] and the ciliary body. [citation needed] The anterior ciliary arteries issue branches to the conjunctiva before piercing the sclera, forming an artieral network in the limbal conjunctiva. They also issue branches to the episclera. [2]