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[34] [35] Bitter oranges (such as the Seville oranges often used in marmalade) can interfere with drugs [38] including etoposide, a chemotherapy drug, some beta blocker drugs used to treat high blood pressure, and cyclosporine, taken by transplant patients to prevent rejection of their new organs. [12] Evidence on sweet oranges is more mixed. [11]
For example, when the blood pressure drug felodipine is taken with grapefruit juice rather than water, levels of the medication in the blood can more than double and result in headache, irregular ...
According to Harvard Health Publishing, grapefruit can be dangerous when combined with drugs used for high blood pressure, high cholesterol, and depression. Check with your doctor for guidance on ...
Important: If you're taking statins or medications for conditions like high blood pressure, cholesterol, heart arrhythmia, organ transplants, or allergies, it can be dangerous to eat grapefruit.
The DASH diet reduced systolic blood pressure by 6 mm Hg and diastolic blood pressure by 3 mm Hg in patients with high normal blood pressure (formerly called "pre-hypertension"). Those with hypertension dropped by 11 and 6 mm Hg, respectively. These changes in blood pressure occurred with no changes in body weight.
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
A 2016 meta-analysis concluded that grape seed extract, in a dose of under 800 milligrams per day over at least 8 weeks, might help to reduce systolic and diastolic blood pressure. [7] People with metabolic syndrome had a more significant outcome (average of a 8½ mmHg decrease in systolic blood pressure) than in healthy subjects. [7]
Grapefruit contains vitamin C, a powerful antioxidant that can boost the immune system. Dietitians share health benefits and warning about medicine interaction. ... but it is high in the ratio of ...
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