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  2. Neisseria meningitidis - Wikipedia

    en.wikipedia.org/wiki/Neisseria_meningitidis

    Neisseria meningitidis, often referred to as the meningococcus, is a Gram-negative bacterium that can cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis. The bacterium is referred to as a coccus because it is round, and more specifically a diplococcus because of its tendency to form ...

  3. NmVac4-A/C/Y/W-135 - Wikipedia

    en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135

    NmVac4-A/C/Y/W-135 is the commercial name of the polysaccharide vaccine against the bacterium (specifically serogroups A, C, Y, and W-135) that causes meningococcal meningitis. The product, by JN-International Medical Corporation, is designed and formulated to be used in developing countries for protecting populations during meningitis disease ...

  4. Meningococcal disease - Wikipedia

    en.wikipedia.org/wiki/Meningococcal_disease

    10–20% mortality generally. 10% mortality with treatment. Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed meningococcus). [1] It has a high mortality rate if untreated but is vaccine-preventable. [2] While best known as a cause of meningitis, it can also result in sepsis, which is an even ...

  5. Meningococcal vaccine - Wikipedia

    en.wikipedia.org/wiki/Meningococcal_vaccine

    Meningococcal vaccine refers to any vaccine used to prevent infection by Neisseria meningitidis. [9] Different versions are effective against some or all of the following types of meningococcus: A, B, C, W-135, and Y. [9][10] The vaccines are between 85 and 100% effective for at least two years. [9] They result in a decrease in meningitis and ...

  6. Meningitis - Wikipedia

    en.wikipedia.org/wiki/Meningitis

    7.7 million (2019) [9] Deaths. 236,000 (2019) [9] Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. [10] The most common symptoms are fever, intense headache, vomiting and neck stiffness and occasionally photophobia. [1]

  7. Outer membrane protein OpcA - Wikipedia

    en.wikipedia.org/wiki/Outer_membrane_protein_OpcA

    structure summary. Outer membrane adhesin OpcA protein family consists of several Neisseria species specific outer membrane proteins. Neisseria meningitidis causes meningococcal meningitis and sepsis. Opc (formerly called 5C) is one of the major outer membrane proteins and has been shown to play an important role in meningococcal adhesion and ...

  8. Multilocus sequence typing - Wikipedia

    en.wikipedia.org/wiki/Multilocus_sequence_typing

    Multilocus sequence typing (MLST) is a technique in molecular biology for the typing of multiple loci, using DNA sequences of internal fragments of multiple housekeeping genes to characterize isolates of microbial species. The first MLST scheme to be developed was for Neisseria meningitidis, [1] the causative agent of meningococcal meningitis ...

  9. Neisseria - Wikipedia

    en.wikipedia.org/wiki/Neisseria

    Neisseria is a large genus of bacteria that colonize the mucosal surfaces of many animals. Of the 11 species that colonize humans, only two are pathogens, N. meningitidis and N. gonorrhoeae. Neisseria species are Gram-negative bacteria included among the Pseudomonadota, a large group of Gram-negative forms. Neisseria diplococci resemble coffee ...