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  2. FDA issues warning about combined use of opioids and ... - AOL

    www.aol.com/news/2016-09-02-fda-issues-warning...

    The FDA has issued new drug labeling and patient information guidelines cautioning the public about mixing opioids and benzodiazepine products. FDA issues warning about combined use of opioids and ...

  3. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    In September 2020, the US Food and Drug Administration (FDA) required the boxed warning be updated for all benzodiazepine medicines to describe the risks of abuse, misuse, addiction, physical dependence, and withdrawal reactions consistently across all the medicines in the class. [117]

  4. Clobazam - Wikipedia

    en.wikipedia.org/wiki/Clobazam

    In September 2020, the U.S. Food and Drug Administration (FDA) required the boxed warning be updated for all benzodiazepine medicines to describe the risks of abuse, misuse, addiction, physical dependence, and withdrawal reactions consistently across all the medicines in the class.

  5. Opioid agonist therapy - Wikipedia

    en.wikipedia.org/wiki/Opioid_agonist_therapy

    Opioid agonist therapy (OAT) is a treatment in which prescribed opioid agonists are given to patients who live with opioid use disorder (OUD). [1] In the case of methadone maintenance treatment (MMT) , methadone is used to treat dependence on heroin or other opioids , and is administered on an ongoing basis.

  6. List of Schedule IV controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_IV...

    The drug or other substance has a currently accepted medical use in treatment in the United States. Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in schedule III. The complete list of Schedule IV substances is as follows.

  7. Chlordiazepoxide - Wikipedia

    en.wikipedia.org/wiki/Chlordiazepoxide

    Serotonin is closely involved in regulating mood and may be one of the causes of feelings of depression in rats using chlordiazepoxide or other benzodiazepines. [18] In September 2020, the US Food and Drug Administration (FDA) required the boxed warning for all benzodiazepine medicines to be updated to describe the risks of abuse, misuse ...

  8. Benzodiazepine dependence - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_dependence

    In the case of benzodiazepine dependence, the continued use seems to be typically associated with the avoidance of unpleasant withdrawal reaction rather than with the pleasurable effects of the drug. [1] Benzodiazepine dependence develops with long-term use, even at low therapeutic doses, [2] often without the described drug seeking behavior ...

  9. Benzodiazepine use disorder - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_use_disorder

    Little attention has focused on the degree that benzodiazepines are abused as a primary drug of choice, but they are frequently abused alongside other drugs of abuse, especially alcohol, stimulants and opiates. [16] The benzodiazepine most commonly abused can vary from country to country and depends on factors including local popularity as well ...