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A colorectal polyp is a polyp (fleshy growth) occurring on the lining of the colon or rectum. [1] Untreated colorectal polyps can develop into colorectal cancer. [2] Colorectal polyps are often classified by their behaviour (i.e. benign vs. malignant) or cause (e.g. as a consequence of inflammatory bowel disease).
Villous adenomas have been demonstrated to contain malignant portions in about 15–25% of cases, approaching 40% in those over 4 cm in diameter. [7] Colonic resection may be required for large lesions. These can also lead to secretory diarrhea with large volume liquid stools with few formed elements.
Traditional serrated adenoma seen under microscopy with H&E stain, showing serrated crypts. SPS may occur with one of two phenotypes: distal or proximal. [6] The distal phenotype may demonstrate numerous small polyps in the distal colon and rectum, whereas the proximal phenotype may be characterized by relatively fewer, but larger polyps in the proximal colon (cecum, ascending colon, etc.). [6]
One’s biological age, which measures the body’s physiological state, may help predict who is at risk for developing colon polyps, a known risk factor for colorectal cancer.
While colon polyps are not commonly associated with symptoms, occasionally they may cause rectal bleeding, and on rare occasions pain, diarrhea or constipation. [9] They are a concern because of the potential for colon cancer being present microscopically, and the risk of benign colon polyps becoming malignant over time. [10]
This can result in the formation of colon polyps, which the Mayo Clinic defines as small clumps of cells that form on the lining of the colon. In the early stages these polyps can be benign, but ...
Gardner's syndrome (also known as Gardner syndrome, familial polyposis of the colon, [1] or familial colorectal polyposis [2]) is a subtype of familial adenomatous polyposis (FAP). Gardner syndrome is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with tumors outside the colon. [3]
Colorectal cancer rates in people under 55 are increasing and it's more advanced. Experts are unsure why, but think diet, exercise and environment play a role.