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Metoidioplasty, metaoidioplasty, or metaidoioplasty [2] (informally called a meto or meta) is a female-to-male gender-affirming surgery. [ 3 ] Testosterone replacement therapy gradually enlarges the clitoris to a mean maximum size of 4.6 cm (1.8 in) [ 4 ] (as the clitoris and the penis are developmentally homologous ).
On the other hand, in obstetrics and gynecology medical literature, a frequent definition of clitoromegaly is when there is a clitoral index (product of lengthwise and crosswise measurements) of greater than 35 mm 2 (0.05 inches 2), which is almost twice the size given above for an average sized clitoris.
Pseudohermaphroditism is an outdated [1] term for when an individual's gonads were mismatched with their internal reproductive system and/or external genitalia. The term was contrasted with "true hermaphroditism" (now known as ovotesticular syndrome), a condition describing an individual with both female and male reproductive gonadal tissues.
Two different genes, each with five exons and four introns, designated as SRD5A1 and SDR5A2, encode two different 5α-reductases. The human 5α-reductase-2 gene (SRD5A2) is located on the short arm of chromosome 2 at band 23 and encodes a 254 amino acid protein, called 5α-reductase type 2.
XX male syndrome, also known as de la Chapelle syndrome, is a rare intersex condition in which an individual with a 46,XX karyotype develops a male phenotype. [2] Synonyms for XX male syndrome include 46,XX testicular difference of sex development (or 46,XX DSD) [3] [4] [5] [6]
[1] They state that hebephilia is a malfunction of the biological mechanism which drives males to be attracted to sexually mature females, and that while typical men are attracted to youthfulness, they are also interested in cues of sexual maturity (adult size, fully developed breasts, and a waist-to-hip ratio of around 0.70). [1]
Female-to-male sex reassignment [ edit ] Although different models of penile prostheses have been reported to be implanted after phalloplasty procedures, [ 24 ] with the first case described in 1978 by Pucket and Montie, [ 25 ] the first penile implants designed and produced specifically for female-to-male gender reassignment surgery for trans ...
[9] [10] Studies also indicate associations between the average age of thelarche and race. [3] [5] The average age of thelarche for African American females in the United States is between 8.9 and 9.5 years, the average for Caucasians is 10–10.4 years, and the average age of thelarche for Hispanic females is approximately 9.8 years.