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Pernicious anemia, one of the causes of vitamin B12 deficiency, is an autoimmune condition that prevents your body from absorbing vitamin B12. Left untreated, pernicious anemia can cause serious medical issues, including irreversible damage to your nervous system.
Treatment for pernicious anemia involves vitamin B12 injections to restore levels to an optimal range, followed by continued injections or oral medications to maintain these levels.
A long time ago, pernicious anemia was fatal (“pernicious” means "deadly"). These days it’s easily treated with B12 pills or shots. With treatment, you can live without symptoms.
Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms. Intramuscular therapy leads to more...
Injections are the preferred method of treating Pernicious Anaemia. Here’s what the BSH Guidelines for Cobalamin (B12) and Folate Disorders say:
Injections are the preferred method of treatment. Initial treatment with oral cobalamin may not be appropriate in Pernicious Anaemia, but may be considered in maintenance or correction of suboptimal levels in asymptomatic patients. 1
Vitamin deficiency anemia is treated with doses of whichever vitamin is lacking. For pernicious anemia, vitamin B-12 is usually delivered via injection and may need to be taken regularly for the rest of your life.
The treatment of pernicious anemia is straightforward. Affected people must take vitamin B12 to remedy their deficiency. This is often done as a series of injections into a muscle, with decreasing frequency over a period of months.
Treatment. The goal of treatment is to increase your vitamin B12 level: Treatment involves a shot of vitamin B12 once a month. People with severely low levels of B12 may need more shots in the beginning. Some people may be adequately treated by taking large doses of vitamin B12 supplements by mouth.
Pernicious anemia usually is easy to treat with vitamin B12 shots or pills. If you have severe pernicious anemia, your doctor may recommend shots first. Shots usually are given in a muscle every day or every week until the level of vitamin B12 in your blood increases.