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The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989 by a group led by pharmacologist David Bailey. Their first published clinical report on grapefruit drug interactions was in 1991. [9] The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit ...
However, just a single glass of grapefruit juice can block this enzyme and interfere with your body's process of breaking down the medication. "This causes medication levels to remain higher and ...
Grapefruit juice is the juice from grapefruits. It is rich in vitamin C and ranges from sweet-tart to very sour. Variations include white grapefruit, pink grapefruit and ruby red grapefruit juice. [1][2] Grapefruit juice is important in medicine because of its interactions with many common drugs including caffeine and medications, which can ...
The fruit is large, 15–25 cm (6–10 in) in diameter, [5] usually weighing 1–2 kilograms (2–4 pounds). It has a thicker rind than a grapefruit, [4] and is divided into 11 to 18 segments. The flesh tastes like mild grapefruit, with a little of its common bitterness (the grapefruit is a hybrid of the pomelo and the orange).
Grapefruit is a citrus hybrid that originated in Barbados in the 18th century. It is an accidental cross between the sweet orange (C. × sinensis) and the pomelo or shaddock (C. maxima), both of which were introduced from Asia in the 17th century. [2] It has also been called the forbidden fruit. [1]
1.500 metres. World University Games. 1967 Tokyo. 1.500 metres. David George Bailey (March 17, 1945 – August 27, 2022) was a Canadian track and field athlete, and subsequently a recognized pharmacologist, who pioneered the research of grapefruit–drug interactions .
If it has not already been done, I support a redirect from "Citrus-drug interactions" to the grapefruit-drug interactions page. Aglo123 13:28, 13 July 2017 (UTC) Too soon Grapefruit is currently the largest contributor to adverse fruit-drug interactions, by far. 129.252.69.40 19:02, 13 July 2017 (UTC)
Under normal circumstances, the grapefruit juice effect is considered to be a negative interaction, and patients are often warned not to consume grapefruit or its juice when taking medication. However, some current research is focused on the potential benefits of cytochrome P450 inhibition. [ 3 ]