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The brain parenchyma refers to the functional tissue in the brain that is made up of the two types of brain cell, neurons and glial cells. [7] It is also known to contain collagen proteins. [8] Damage or trauma to the brain parenchyma often results in a loss of cognitive ability or even death.
Information about the structure and function of the human brain comes from a variety of experimental methods, including animals and humans. Information about brain trauma and stroke has provided information about the function of parts of the brain and the effects of brain damage. Neuroimaging is used to visualise the brain and record brain ...
The astrocytes of the glia limitans are responsible for separating the brain into two primary compartments. The first compartment is the immune-privileged brain and spinal cord parenchyma. This compartment contains multiple immunosuppressive cell surface proteins such as CD200 and CD95L and it allows for the release of anti-inflammatory factors.
Furthermore, tracing the outflow of compounds injected into the brain parenchyma have indicated that meningeal lymphatics function downstream of the glymphatic system. Genetically engineered mice which lack the meningeal lymphatic vessels demonstrated attenuated clearance of macromolecules from the brain.
This development section covers changes in brain structure over time. It includes both the normal development of the human brain from infant to adult and genetic and evolutionary changes over many generations. Neural development in humans; Neuroplasticity – changes in a brain due to behavior, environment, aging, injury etc.
Brain at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (view tree for regions of the brain) BrainMaps.org; BrainInfo (University of Washington) "Brain Anatomy and How the Brain Works". Johns Hopkins Medicine. 14 July 2021. "Brain Map". Queensland Health. 12 July 2022.
In anatomy in general and neuroanatomy in particular, several sets of topographic terms are used to denote orientation and location, which are generally referred to the body or brain axis (see Anatomical terms of location). The axis of the CNS is often wrongly assumed to be more or less straight, but it actually shows always two ventral ...
The pathway consists of a para-arterial influx mechanism for CSF driven primarily by arterial pulsation [2], which "massages" the low-pressure CSF into the denser brain parenchyma, and the CSF flow is regulated during sleep by changes in parenchyma resistance due to expansion and contraction of the extracellular space.