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The cloverleaf model of tRNA is a model that depicts the molecular structure of tRNA. [1] The model revealed that the chain of tRNA consists of two ends—sometimes called "business ends"—and three arms.
The range of conformations adopted by tRNA as it transits the A/T through P/E sites on the ribosome. The Protein Data Bank (PDB) codes for the structural models used as end points of the animation are given. Both tRNAs are modeled as phenylalanine-specific tRNA from Escherichia coli, with the A/T tRNA as a homology model of the deposited ...
A tRNA molecule from yeast. Anticodon (triplet sequence in red) is the mRNA-binding site during protein synthesis. The adaptor hypothesis was framed to explain how information could be extracted from a nucleic acid and used to put together a string of amino acids in a specific sequence, that sequence being determined by the nucleotide sequence ...
There are many secondary structure elements of functional importance to biological RNAs; some famous examples are the Rho-independent terminator stem-loops and the tRNA cloverleaf. Active research is on-going to determine the secondary structure of RNA molecules, with approaches including both experimental and computational methods (see also ...
In 1965, Holley et al. purified and sequenced the first tRNA molecule, initially proposing that it adopted a cloverleaf structure, based largely on the ability of certain regions of the molecule to form stem loop structures. [60] The isolation of tRNA proved to be the first major windfall in RNA structural biology.
Most of the U.S. will enjoy milder temperatures on Thursday, but the warmup will be brief as a polar vortex will send temperatures tumbling below freezing for most of the nation starting this weekend.
Last week, Ina Garten shared a super-cozy dinner party menu on Instagram. It featured a crispy potato galette, lemony skillet-roasted chicken and, for dessert, salted caramel brownies. I mean, yum ...
Student says he was banned from going to class after protesting. The lead plaintiff in the lawsuit, filed in U.S. District Court for the Eastern District of Michigan, is Jonathan Zou, a sophomore ...