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In some cases this accumulation can mimic a liver tumor. Sometimes the opposite phenomenon can be seen, that is an "island" of normal parenchyma in a “shining” liver. In both cases ultrasound examination identifies a well defined, un-encapsulated area, with echostructure and vasculature similar to those of normal liver parenchyma.
The liver parenchyma is the functional tissue of the organ made up of around 80% of the liver volume as hepatocytes. The other main type of liver cells are non-parenchymal. Non-parenchymal cells constitute 40% of the total number of liver cells but only 6.5% of its volume. [11]
On ultrasound, HCC often appears as a small hypoechoic lesion with poorly defined margins and coarse, irregular internal echoes. When the tumor grows, it can sometimes appear heterogeneous with fibrosis, fatty change, and calcifications. This heterogeneity can look similar to cirrhosis and the surrounding liver parenchyma.
The liver can be imaged by swiping the probe sagittally from medial to lateral at the subcoastal region. However, if majority of the liver parenchyma is located high up in behind the ribs, the subject can be asked to breathe deeply to push down the liver into the abdomen for better visibility of liver.
Liver cell adenomatosis is also associated with becoming hepatocellular carcinoma. [11] Like hepatic adenomas, they are diagnosed with imaging and biopsies as needed. Treatment of liver cell adenomatosis is difficult due to the multiple, widespread lesions. Liver imaging should be reviewed to see if it is possible to surgically remove the ...
The main liver cells are called hepatocytes; however, there are other cells that can be observed in a liver sample such as Kupffer cells (macrophages). [2] The liver is the biggest gland of the body. It has a wide variety of functions that range from the destruction of old blood cells to the control of the whole metabolism of macromolecules . [ 3 ]
Liver cancer can be primary in which the cancer starts in the liver, or it can be liver metastasis, or secondary, in which the cancer spreads from elsewhere in the body to the liver. Liver metastasis is the more common of the two liver cancers. [3] Instances of liver cancer are increasing globally. [8] [9]
Apoptosis of the liver of a mouse. Hepatocytes are the liver's primary parenchymal cells, forming 80% of the liver's mass and 60% of its cells. They are round in shape and contain a nucleus and organelles that contribute to metabolic and secretory functions. [5] Hepatocytes also play a pivotal role in liver inflammation. [6]