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The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose. It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect . [ 1 ]
inducing pioneering research and development of new drugs and; enabling competitors to bring low-cost, generic copies of those drugs to market'". [1] The Orange Book identifies drug products approved on the basis of safety and effectiveness by the Food and Drug Administration (FDA) under the Federal Food, Drug, and Cosmetic Act.
high risk, early-stage triple-negative breast cancer: Avalglucosidase alfa: Genzyme: late-onset Pompe disease: Lenvatinib: Eisai Inc: advanced renal cell carcinoma, used in combination with pembrolizumab: Difelikefalin: Cara Therapeutics: pruritis related to hemodialysis in chronic kidney disease: Mobocertinib: Takeda Pharmaceuticals
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication. The list is not exhaustive and not all drugs are used regularly in all countries.
Specialty drugs or specialty pharmaceuticals are a recent designation of pharmaceuticals [1] [2] classified as high-cost, [3] [4] [5] high complexity and/or high touch. [4] Specialty drugs are often biologics [ 3 ] [ 6 ] —"drugs derived from living cells" [ 7 ] that are injectable or infused (although some are oral medications). [ 4 ]
Geroscience has a long way to go, but there are four FDA-approved drugs that have shown promise to “target the process of aging,” Barzilai says. While not approved as anti-aging treatments ...
Semaglutide for weight loss has been in shortage since 2022, according to the FDA’s drug shortage database.Tirzepatide, which was approved for weight loss in the U.S. only in November, went into ...
The risk of bleeding is increased if used at the same time as other blood thinning drugs such as nonsteroidal anti-inflammatory drugs, antiplatelet drugs and heparin. [2] The blood thinning effects can be reduced if used at the same time as rifampicin and phenytoin , and increased with fluconazole .