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Congenital pulmonary airway malformation (CPAM), formerly known as congenital cystic adenomatoid malformation (CCAM), is a congenital disorder of the lung similar to bronchopulmonary sequestration. In CPAM, usually an entire lobe of lung is replaced by a non-working cystic piece of abnormal lung tissue.
Chest x-ray of infant showing CPAM in the left lung causing a mediastinal shift towards the right. The cysts appear as bubbles in the left lung. Congenital pulmonary airway malformation (CPAM) is a rare disease in which the lung airways develop abnormally in the fetus. This leads to infants having pockets of air and cystic masses in their lungs.
Congenital lobar emphysema (CLE), also known as congenital lobar overinflation and infantile lobar emphysema, [37] is a neonatal condition associated with enlarged air spaces in the lungs of newborn infants. It is diagnosed around the time of birth or in the first 6 months of life, occurring more often in boys than girls.
Low magnification micrograph of pneumatosis intestinalis in bowel wall.. Pneumoperitoneum (or peritoneal emphysema), air or gas in the abdominal cavity.The most common cause is a perforated abdominal viscus, generally a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma.
Pulmonary interstitial emphysema often resolves gradually and may take 2–3 weeks. [2] For longer durations of PIE the length of time of mechanical ventilation needed may increase and the incidence of bronchopulmonary dysplasia becomes higher. Some infants may develop chronic lobar emphysema, which may require surgical lobectomies. [3]
In children, additional causes include measles, echinococcosis, inhalation of a foreign body, and certain congenital malformations (congenital pulmonary airway malformation and congenital lobar emphysema). [19] 11.5% of people with a spontaneous pneumothorax have a family member who has previously experienced a pneumothorax.
These include normal variation, left ventricular hypertrophy, conduction defects, inferior wall myocardial infarction, preexcitation syndrome, ventricular ectopic rhythms, congenital heart disease, hyperkalemia, emphysema, mechanical shift and pacemaker-generated paced rhythm. Normal variation causing LAD is an age-related physiologic change.
These are the first heart sound (S 1) and second heart sound (S 2), produced by the closing of the atrioventricular valves and semilunar valves, respectively. In addition to these normal sounds, a variety of other sounds may be present including heart murmurs , adventitious sounds , and gallop rhythms S 3 and S 4 .