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Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. [6] . It may be used to prevent mother-to-child spread during birth or after a needlestick injury or other potential exposure. [6] .
Through a drug screening initiative launched in the fall, the British pharmaceutical company Burroughs-Wellcome found evidence that AZT could suppress viral replication in mouse studies.
The first AIDS drug was approved on March 19, 1987—but getting there was by no means easy. Here's the story behind the treatment.
Zidovudine (also known as AZT) is used together with other medicines for the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
AZT, drug used to delay development of AIDS (acquired immunodeficiency syndrome) in patients infected with HIV (human immunodeficiency virus). AZT belongs to a group of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).
Zidovudine is a medication used in the management and treatment of HIV-1. It is in the nucleoside reverse transcriptase inhibitor class of medications. This activity reviews the indications, mechanism of action, and contraindications for zidovudine as a valuable agent in the treatment of HIV-1.
INDICATIONS. FDA. Treatment of HIV infection in combination with other antiretrovirals. FORMS. *Prices represent cost per unit specified, are representative of "Average Wholesale Price" (AWP). ^Dosage is indicated in mg unless otherwise noted. USUAL ADULT DOSING. Pill burden: 2 per day.
Adults—300 milligrams (mg) 2 times a day in combination with other anti-HIV medicines. Children and infants 4 weeks of age and older—Dose is based on body weight or body size and must be determined by your child's doctor.
Zidovudine (brand name: Retrovir) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the following uses: To treat HIV infection in adults, children, and infants. When zidovudine is used to treat HIV infection, the medicine is always used in combination with other HIV medicines.
Zidovudine (also known as AZT) injection is used together with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).