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  2. Richter's transformation - Wikipedia

    en.wikipedia.org/wiki/Richter's_transformation

    Richter's transformation (RT), also known as Richter's syndrome, is the conversion of chronic lymphocytic leukemia (CLL) or its variant, small lymphocytic lymphoma (SLL), into a new and more aggressively malignant disease. [1] CLL is the circulation of malignant B lymphocytes with or without the infiltration of these cells into lymphatic or ...

  3. Post-transplant lymphoproliferative disorder - Wikipedia

    en.wikipedia.org/wiki/Post-transplant_lymphopro...

    Post-transplant lymphoproliferative disorder ( PTLD) is the name given to a B cell proliferation due to therapeutic immunosuppression after organ transplantation. These patients may develop infectious mononucleosis-like lesions or polyclonal polymorphic B-cell hyperplasia. Some of these B cells may undergo mutations which will render them ...

  4. Follicular lymphoma - Wikipedia

    en.wikipedia.org/wiki/Follicular_lymphoma

    Follicular lymphoma ( FL) is a cancer that involves certain types of white blood cells known as lymphocytes. The cancer originates from the uncontrolled division of specific types of B-cells known as centrocytes and centroblasts. These cells normally occupy the follicles (nodular swirls of various types of lymphocytes) in the germinal centers ...

  5. Hematopoietic stem cell transplantation - Wikipedia

    en.wikipedia.org/wiki/Hematopoietic_stem_cell...

    In 1975, John Kersey, also of the University of Minnesota, performed the first successful bone-marrow transplant to cure lymphoma. His patient, a 16-year-old-boy, is today the longest-living lymphoma transplant survivor. Donor registration and recruitment

  6. Lymphoma - Wikipedia

    en.wikipedia.org/wiki/Lymphoma

    Lymphoma. Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell ). [7] The name typically refers to just the cancerous versions rather than all such tumours. [7] Signs and symptoms may include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, and constantly feeling ...

  7. Anaplastic large-cell lymphoma - Wikipedia

    en.wikipedia.org/wiki/Anaplastic_large-cell_lymphoma

    Micrograph of an anaplastic large-cell lymphoma. H&E stain. Anaplastic large-cell lymphoma ( ALCL) refers to a group of non-Hodgkin lymphomas in which aberrant T cells proliferate uncontrollably. Considered as a single entity, ALCL is the most common type of peripheral lymphoma [1] and represents ~10% of all peripheral lymphomas in children. [2]

  8. X-linked lymphoproliferative disease - Wikipedia

    en.wikipedia.org/wiki/X-linked_lymphoproliferat...

    Care differs depending on the phenotype of XLP expressed, with treatments varying between those experiencing HLH or lymphoma, and whether or not they have been infected with EBV. Still, a bone marrow transplant that includes CD34+ hematopoietic stem cells is the only known treatment for the disorder as a whole. Patients who cannot find a bone ...

  9. Lymphoproliferative disorders - Wikipedia

    en.wikipedia.org/wiki/Lymphoproliferative_disorders

    Lymphoproliferative disorders are a set of disorders characterized by the abnormal proliferation of lymphocytes into a monoclonal lymphocytosis. The two major types of lymphocytes are B cells and T cells, which are derived from pluripotent hematopoietic stem cells in the bone marrow. Individuals who have some sort of dysfunction with their ...

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