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  2. Valaciclovir - Wikipedia

    en.wikipedia.org/wiki/Valaciclovir

    Herpes zoster (shingles): the typical dosage for treatment of herpes is 1,000 mg orally three times a day for seven consecutive days. [10] Prevention of cytomegalovirus following organ transplantation; Prevention of herpesviruses in immunocompromised people (such as those undergoing cancer chemotherapy) [11] Chickenpox in children (ages 2–18) [1]

  3. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    On the first day, they'd have 100 mg in their system; their body would clear 10 mg, leaving 90 mg. On the second day, the patient would have 190 mg in total; their body would clear 19 mg, leaving 171 mg. On the third day, they'd be up to 271 mg total; their body would clear 27 mg, leaving 244 mg.

  4. Aciclovir - Wikipedia

    en.wikipedia.org/wiki/Aciclovir

    Studies in rats in which they were given the equivalent to 63 times the standard steady-state human concentrations of the drug [Note 1] on day 10 of gestation showed head and tail anomalies. [ 27 ] Aciclovir is recommended by the CDC for treatment of varicella during pregnancy, especially during the second and third trimesters.

  5. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    Classically, for clinical indications of an approved drug, TI refers to the ratio of the dose of the drug that causes adverse effects at an incidence/severity not compatible with the targeted indication (e.g. toxic dose in 50% of subjects, TD 50) to the dose that leads to the desired pharmacological effect (e.g. efficacious dose in 50% of ...

  6. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    Rank Brand Name(s) Generic Name Sales Q1 2014 Sales ($000) Change from Q4 2013 Company(ies) Disease/Medical Use First Approval Date Patent Expiration Date [6] [7]; 1: Abilify

  7. Herpangina - Wikipedia

    en.wikipedia.org/wiki/Herpangina

    A diagnosis can be made from clinical signs and symptoms, and treatment consists of minimizing the discomfort of symptoms. [5] It can be differentiated from herpetic gingivostomatitis by the positioning of vesicles - in herpangina, they are typically found on the posterior oropharynx, as compared to gingivostomatitis where they are typically found on the anterior oropharynx and the mouth.

  8. Sun shoots out biggest solar flare in nearly a decade, but ...

    www.aol.com/news/sun-shoots-biggest-solar-flare...

    The sun produced its biggest flare in nearly a decade Tuesday, just days after severe solar storms pummeled Earth and created dazzling northern lights in unaccustomed places. “Not done yet ...

  9. May 2024 solar storms - Wikipedia

    en.wikipedia.org/wiki/May_2024_solar_storms

    The solar storms of May 2024 (also known as 2024 Mother's Day solar storm [1] or Gannon storm in memory of Jennifer Gannon, [2] a space weather physicist [3]) were a series of powerful solar storms with extreme solar flares and geomagnetic storm components that occurred from 10–13 May 2024 during solar cycle 25.