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  2. Mesomeric effect - Wikipedia

    en.wikipedia.org/wiki/Mesomeric_effect

    The mesomeric effect as a result of p-orbital overlap (resonance) has absolutely no effect on this inductive effect, as the inductive effect has purely to do with the electronegativity of the atoms and their topology in the molecule (which atoms are connected to which). Specifically the inductive effect is the tendency for the substituents to ...

  3. Electrophilic aromatic directing groups - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_aromatic...

    However, another effect that plays a role is the +M effect which adds electron density back into the benzene ring (thus having the opposite effect of the -I effect but by a different mechanism). This is called the mesomeric effect (hence +M) and the result for fluorine is that the +M effect approximately cancels out the -I effect.

  4. Resonance (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Resonance_(chemistry)

    Contributing structures of the carbonate ion. In chemistry, resonance, also called mesomerism, is a way of describing bonding in certain molecules or polyatomic ions by the combination of several contributing structures (or forms, [1] also variously known as resonance structures or canonical structures) into a resonance hybrid (or hybrid structure) in valence bond theory.

  5. Hammett equation - Wikipedia

    en.wikipedia.org/wiki/Hammett_equation

    This effect is depicted in scheme 3, where, in a para substituted arene 1a, one resonance structure 1b is a quinoid with positive charge on the X substituent, releasing electrons and thus destabilizing the Y substituent. This destabilizing effect is not possible when X has a meta orientation. Scheme 3. Hammett Inductive Mesomeric Effects

  6. Phenyl group - Wikipedia

    en.wikipedia.org/wiki/Phenyl_group

    It is often said the resonance stability of phenol makes it a stronger acid than that of aliphatic alcohols such as ethanol (pK a = 10 vs. 16–18). However, a significant contribution is the greater electronegativity of the sp 2 alpha carbon in phenol compared to the sp 3 alpha carbon in aliphatic alcohols.

  7. Hyperconjugation - Wikipedia

    en.wikipedia.org/wiki/Hyperconjugation

    A portion of Kistiakowsky's work involved a comparison of other unsaturated compounds in the form of CH 2 =CH(CH 2)n-CH=CH 2 (n=0,1,2). These experiments revealed an important result; when n=0, there is an effect of conjugation to the molecule where the ΔH value is lowered by 3.5 kcal. This is likened to the addition of two alkyl groups into ...

  8. Reimer–Tiemann reaction - Wikipedia

    en.wikipedia.org/wiki/Reimer–Tiemann_reaction

    Chloroform (1) is deprotonated by a strong base (normally hydroxide) to form the chloroform carbanion (2) which will quickly alpha-eliminate to give dichlorocarbene (3); this is the principal reactive species. The hydroxide will also deprotonate the phenol (4) to give a negatively charged phenoxide (5). The negative charge is delocalised into ...

  9. Azo coupling - Wikipedia

    en.wikipedia.org/wiki/Azo_coupling

    In organic chemistry, an azo coupling is an reaction between a diazonium compound (R−N≡N +) and another aromatic compound that produces an azo compound (R−N=N−R’).In this electrophilic aromatic substitution reaction, the aryldiazonium cation is the electrophile, and the activated carbon (usually from an arene, which is called coupling agent), serves as a nucleophile.