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Sulfadimethoxine (or sulphadimethoxine, trade names Di-Methox or Albon) is a long-lasting sulfonamide antimicrobial medication used in veterinary medicine. It is used to treat many infections, including respiratory, urinary tract, enteric, and soft tissue infections [3] and can be given as a standalone or combined with ormetoprim to broaden the target range. [2]
Marbofloxacin is a carboxylic acid derivative third generation fluoroquinolone antibiotic. It is used in veterinary medicine under the brand names Marbocyl, Forcyl, Marbo vet and Zeniquin. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon (CAS number 115550-35-1).
Pradofloxacin, sold under the brand name Veraflox among others, is a third-generation enhanced spectrum veterinary antibiotic of the fluoroquinolone class. [5] It was developed by Elanco Animal Health GmbH and received approval from the European Commission in April 2011, for prescription-only use in veterinary medicine for the treatment of bacterial infections in dogs and cats.
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Streptococcus canis is a group G beta-hemolytic species of Streptococcus. [1] It was first isolated in dogs, giving the bacterium its name. These bacteria are characteristically different from Streptococcus dysgalactiae, which is a human-specific group G species that has a different phenotypic chemical composition.
Antibiotic candidates Generic name Origin Susceptible phyla Stage of development Mechanism of action Unclassified Teixobactin: Eleftheria terrae: Gram-positive, including antibiotic resistant S. aureus and M. tuberculosis: No human trials scheduled: Binds fatty acid precursors to cell wall Malacidins: Uncultured Bacterium
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It is also one of the leading causes of bacterial skin and soft tissue infections, [31] [30] such as pyoderma, urinary tract infections, [32] and surgical site infections. [31] [2] It is also known to infect cats, although not as common. [33] It is transferred by animal-animal contact, and some dog-human zoonoses have also been reported. [20]
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