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Unlike modafinil, adrafinil does not have FDA approval and was withdrawn from the French market in 2011. [169] The FDA approved modafinil in 1998 for narcolepsy treatment, and later for shift work sleep disorder and obstructive sleep apnea in 2003. [8] [170] [171] It was approved in the UK in December 2002.
A Cephalon-founded study in which patients were administered modafinil, methylphenidate, and a placebo found that modafinil produces "psychoactive and euphoric effects and feelings consistent with [methylphenidate]." [12] Like modafinil, armodafinil is an inhibitor and/or inducer of certain cytochrome P450 enzymes.
Modafinil is a drug that helps keep people awake and alert (wakefulness-promoting agent or "eugeroic"). [ 1 ] [ 2 ] Most of the listed modafinil analogues are drugs that specifically target dopamine reuptake (reabsorption of a neurotransmitter by a neurotransmitter transporter ) with stronger effects ( selective DRIs with improved potency ...
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This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication.
The drug or other substance has a low potential for abuse relative to the drugs or ... [10] 2749 Camazepam [10] 8192 ... [10] 2887 Triazolam [25] 2781 Zaleplon [26 ...
The pharmaceutical company Cephalon, the original United States market rights holder of modafinil, has demonstrated initiative in the development of a successor to the prototypical eugeroic. [25] Of the more than twenty compounds preclinically tested in Cephalon's three-part drug discovery series, the compound fluorenol was selected as a lead. [26]
In the United States military, modafinil has been approved for use on certain Air Force missions, and it is being investigated for other uses. [19] As of November 2012, modafinil is the only drug approved by the Air Force as a "go pill" for fatigue management. [20] The use of dextroamphetamine (a.k.a., Dexedrine) is no longer approved. [20] Yes ...
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