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Stage IV: The lymphoma is in one or more organs beyond the lymphatic system, such as the liver, lungs, bone marrow, or cerebrospinal fluid. [2] A patient's stage may be determined through blood tests, bone marrow biopsy, chest X-rays, computed tomography (CT) scans, positron emission tomography (PET) scans, and magnetic resonance imaging (MRI).
Micrograph showing Hodgkin's lymphoma, a type of B cell lymphoma that is usually considered separate from other B cell lymphomas. Field stain. CT scan of primary B cell lymphoma in the left ilium, as diffuse cortical and trabecular thickening of the hemipelvis, mimicking Paget's disease. [2] There are numerous kinds of lymphomas involving B cells.
[3] [13] [14] Diagnosis, if enlarged lymph nodes are present, is usually by lymph node biopsy. [1] [2] Blood, urine, and bone marrow testing may also be useful in the diagnosis. [2] Medical imaging may then be done to determine if and where the cancer has spread. [1] [2] Lymphoma most often spreads to the lungs, liver, and brain. [1] [2]
Modern detail-oriented scans such as high-resolution computed tomography (HRCT) is the gold standard in respiratory medicine and thoracic surgery for investigating disorders of the lung parenchyma . Contrasted CT scans of the chest are usually used to confirm diagnosis of for lung cancer and abscesses , as well as to assess lymph node status at ...
Hodgkin lymphoma (HL) is a type of lymphoma in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the patient's lymph nodes.
The final diagnosis was non-Hodgkin lymphoma at both sites. If there is an intermediate risk of malignancy, further imaging with positron emission tomography (PET scan) is appropriate (if available). It can be done simultaneously as a CT scan in the form of PET-CT.
The diagnosis is usually suspected following a CT scan. Typical features on CT include solid and sub-solid nodules, ground glass change and reticulation. [7] There may be features of multi-system involvement such as adenopathy and splenomegaly. [citation needed] The commonest abnormality on lung function testing is a decrease in gas transfer. [2]
In radiology, the tree-in-bud sign is a finding on a CT scan that indicates some degree of airway obstruction. [1] The tree-in-bud sign is a nonspecific imaging finding that implies impaction within bronchioles, the smallest airway passages in the lung.