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Cardiovascular agents are drugs that affect the rate and intensity of cardiac contraction, blood vessel diameters, blood volume, blood clotting and blood cholesterol levels. [1] They are indicated to treat diseases related to the heart or the vascular system (blood vessels), such as hypertension , hyperlipidemia , coagulation disorders , heart ...
[1] [2] Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus). In the U.S., the American College of Chest Physicians publishes clinical guidelines for clinicians for the use of these drugs to treat and prevent a variety of diseases. [citation ...
Antiplatelet drugs are widely used in primary and secondary prevention of thrombotic disease, especially myocardial infarction and ischemic stroke. [1] Antiplatelet therapy with one or more of these drugs decreases the ability of blood clots to form by interfering with the platelet activation process in primary hemostasis. Antiplatelet drugs ...
Dipyridamole (trademarked as Persantine and others) is an antiplatelet drug of the nucleoside transport inhibitor and PDE3 inhibitor class that inhibits blood clot formation when given chronically and causes blood vessel dilation when given at high doses over a short time.
These drugs antagonize the P2Y 12 platelet receptors and therefore prevent the binding of ADP to the P2Y 12 receptor. This leads to a decrease in aggregation of platelets, prohibiting thrombus formation. The P2Y 12 receptor is a surface bound protein found on blood platelets.
Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying blood clotting) by directly inhibiting the enzyme thrombin (factor IIa). Some are in clinical use, while others are undergoing clinical development.
Neurodegenerative diseases. Lipid disorders. ... Drugs or supplements that lower blood pressure. Blood thinners or other drugs or supplements that slow blood clotting.
While the drug is described as a "blood thinner", it does not reduce viscosity but rather prevents blood clots from forming (coagulating). Accordingly, it is commonly used to prevent deep vein thrombosis and pulmonary embolism , and to protect against stroke in people who have atrial fibrillation , valvular heart disease , or artificial heart ...