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Prolactin-induced protein has also been used for identification and detection of disseminated breast cancer cells. [20] The PIP gene is amplified in some breast cancer lines accounting for some of its overexpression, however additional mechanisms are needed to completely explain its overexpression. [21]
Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...
Pokemon is the name given to the protein product of Zbtb7 gene by the research team at Memorial Sloan Kettering Cancer Center (MSKCC), which discovered its oncogenic function. It stands for " POK e rythroid m yeloid on togenic [ sic ] [ 13 ] factor" and is most likely a backronym of the Pokémon media franchise .
Nuclear grade describes how closely the nuclei of cancer cells look like the nuclei of normal breast cells; the higher the nuclear grade, the more abnormal appearing the nuclei are and the more aggressive the tumor cells tend to be.) PDCIS has an excellent prognosis with long-term survival rates similar to those for EPC. [2]
Invasive lobular carcinoma (ILC) is breast cancer arising from the lobules of the mammary glands. [1] It accounts for 5–10% of invasive breast cancer. [2] [3] Rare cases of this carcinoma have been diagnosed in men (see male breast cancer). [4]
These classifications are spindle cell, squamous cells, matrix-producing, carcinosarcoma, and MBC with osteoclastic giant cell. Another research group, Oberman et al., proposed a classification system consisting of spindle cell carcinoma, invasive ductal carcinoma with extensive squamous metaplasia, and invasive ductal carcinoma with ...
10647 n/a Ensembl ENSG00000124935 n/a UniProt O95969 n/a RefSeq (mRNA) NM_006551 n/a RefSeq (protein) NP_006542 n/a Location (UCSC) Chr 11: 62.24 – 62.24 Mb n/a PubMed search n/a Wikidata View/Edit Human Secretoglobin family 1D member 2 is a protein that in humans is encoded by the SCGB1D2 gene. Function The protein encoded by this gene is a member of the lipophilin subfamily, part of the ...
Fluid produced by the cells can produce ascites which is typical in carcinomatosis, but less common in peritoneal sarcomatosis. [1] Fluid can be serous as seen in primary peritoneal carcinoma or mucinous such as found in pseudomyxoma peritonei which is typically a tumor derived from the appendix .