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Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [ 3 ] and synovial villous proliferation are often seen.
Other names are primary hypertrophic osteoarthropathy or Touraine-Solente-Golé syndrome. [2] It is mainly characterized by pachyderma (thickening of the skin), periostosis (excessive bone formation) and finger clubbing (swelling of tissue with loss of normal angle between nail and nail bed). [1] [3] This disease affects more men than women.
Examples of periosteal reactive bone in selected specimens of Triceratops. A periosteal reaction can result from a large number of causes, including injury and chronic irritation due to a medical condition such as hypertrophic osteopathy, bone healing in response to fracture, chronic stress injuries, subperiosteal hematomas, osteomyelitis, and cancer of the bone.
A special form of clubbing is hypertrophic pulmonary osteoarthropathy (HPOA), known in continental Europe as Pierre Marie-Bamberger syndrome. This is the combination of clubbing and thickening of periosteum (connective tissue lining of the bones) and synovium (lining of joints), and is often initially diagnosed as arthritis .
Condition Calcium Phosphate Alkaline phosphatase Parathyroid hormone Comments Osteopenia: unaffected unaffected normal unaffected decreased bone mass
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Medical imaging Radiographic systems to classify osteoarthritis vary by which joint is being investigated. In osteoarthritis , the choice of treatment is based on pain and decreased function, but radiography can be useful before surgery in order to prepare for the procedure.
Hyperostosis is an excessive growth of bone.It may lead to exostosis.It occurs in many musculoskeletal disorders.. Disorders featuring hyperostosis include: [1] Camurati-Engelmann disease, type 2