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The prognosis of hydronephrosis is extremely variable and depends on the condition leading to hydronephrosis, whether one (unilateral) or both (bilateral) kidneys are affected, the pre-existing kidney function, the duration of hydronephrosis (acute or chronic), and whether hydronephrosis occurred in developing or mature kidneys. [citation needed]
It is the most common cause of hydronephrosis detected in utero and is the most common anomaly detected on prenatal ultrasounds. [1] [2] It occurs in approximately 1 in every 1500 live births, is most commonly seen in males, involves the left ureter twice as often as the right ureter. [1] [2] UPJ obstruction is transient in most cases. [2]
Okamoto syndrome (OS), also known as Au–Kline syndrome (AKS), is a very rare autosomal dominant genetic condition characterised by congenital hydronephrosis, low muscle tone, heart defects, intellectual disability and characteristic facial features.
Patients can also be treated with alpha blockers [7] in cases where the stone is located in the ureter. A 2019 review found three cases of renal colic were hydronephrosis caused by malpositioned menstrual cups pressing on a ureter. When the cups were removed, the symptoms disappeared. [8]
The various symptoms of acute kidney injury result from the various disturbances of kidney function that are associated with the disease. Accumulation of urea and other nitrogen-containing substances in the bloodstream lead to a number of symptoms, such as fatigue , loss of appetite , headache , nausea , and vomiting . [ 6 ]
Kidney stones are becoming more common with time, and their incidence is believed to increase recently due to unhealthy diet habits. The passage of kidney stones into ureters might lead to their impaction and the development of local inflammatory process around the stone in addition to the obstruction of the ipsilateral kidney and build up of pressure manifested as hydronephrosis.
Urofacial syndrome, or Ochoa syndrome, is an autosomal recessive [1] congenital disorder characterized by an association of a lower urinary tract and bowel dysfunction with a typical facial expression: when attempting to smile, the patient seems to be crying or grimacing.
Posterior urethral valve (PUV) disorder is an obstructive developmental anomaly in the urethra and genitourinary system of male newborns. [1] A posterior urethral valve is an obstructing membrane in the posterior male urethra as a result of abnormal in utero development.