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Zinc gluconate has been used in lozenges for treating the common cold. However, controlled trials with lozenges which include zinc acetate have found it has the greatest effect on the duration of colds. [3] [4] Zinc has also been administered nasally for treating the common cold, but has been reported to cause anosmia in some cases. [5] [6] [7] [8]
Zinc picolinate (or ZnPic) is the zinc coordination complex derived from picolinic acid and zinc(II). It has the formula Zn(NC 5 H 4 CO 2) 2 (H 2 O) 2.The complex adopts an octahedral molecular geometry, containing two bidentate picolinate ligands (conjugate base of picolinic acid) and two aquo ligands.
Zinc supplements (frequently zinc acetate or zinc gluconate lozenges) are a group of dietary supplements that are commonly used in an attempt to treat the common cold. [1] Evidence suggests that zinc does not prevent colds but may reduce their duration, with minimal or no impact on symptom severity. [2] [3] Adverse effects with zinc supplements ...
ATC code A12 Mineral supplements is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Although zinc sulfate is a commonly used zinc form, zinc citrate, gluconate and picolinate may be valid options as well. These forms are better absorbed than zinc oxide. [ 174 ]
Structure of Zn(picolinate) 2 (H 2 O) 2. Hydrogenation of picolinic acid gives piperidine-2-carboxylic acid, a precursor to the drug Mepivacaine. Picolinic acid is a bidentate chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body. [5] [6] It is a substrate in the Mitsunobu reaction.
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