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Clostridioides difficile infection [5] (CDI or C-diff), also known as Clostridium difficile infection, is a symptomatic infection due to the spore-forming bacterium Clostridioides difficile. [6] Symptoms include watery diarrhea, fever, nausea, and abdominal pain. [1] It makes up about 20% of cases of antibiotic-associated diarrhea. [1]
Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [4] [5] It is known also as C. difficile, or C. diff (/ s iː d ɪ f /), and is a Gram-positive species of spore-forming bacteria. [6]
Grade 2 diarrhea is defined by an increase of 4–6 bowel movements per day. Grade 3 diarrhea is defined by an increase by 7 or more bowel movements per day. Grade 4 diarrhea involves life-threatening consequences, such as shock, whereas grade 5 results in death. The extent of colitis is also graded based on severity, from 1 to 5.
Chronic infection of C. difficile, G. lamblia. C. difficile — bacteria that can be the source of diarrhea. [32] G. lamblia — a parasite that can be the source diarrhea. [33] From 1–12 months, typical causes of chronic diarrhea are the following: Acrodermatitis enteropathica, a condition in which the intestine cannot absorb zinc. [16]
Clostridioides difficile, also known more commonly as C. diff, accounts for 10 to 20% of antibiotic-associated diarrhea cases, because the antibiotics administered for the treatment of certain disease processes such as inflammatory colitis also inadvertently kill a large portion of the gut flora, the normal flora that is usually present within the bowel.
C. difficile can cause pseudomembranous colitis in humans, [5] and in hospitalized patients who develop it, fulminant C. difficile colitis is a significant and increasing cause of death. [6] Horses under stress appear to be more susceptible to developing colitis X. [2] Disease onset is often closely associated with surgery or transport. [1]
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