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Microencapsulation is a valuable technique for local, regional and oral delivery of therapeutic products as it can be implanted into numerous tissue types and organs. For prolonged drug delivery to the treatment site, implantation of these drug loaded artificial cells would be more cost effective in comparison to direct drug delivery. Moreover ...
Applications of micro-encapsulation are numerous. It is mainly used to increase the stability and life of the product being encapsulated, facilitate the manipulation of the product and provide for the controlled release of the contents. Microencapsulation is used to preserve vitamin A from the deteriorating effects of oxygen. [2]
Xanomeline is an agonist that primarily targets the muscarinic acetylcholine receptor family of five muscarinic receptor subtypes, which are designated M 1-M 5. [2] While it binds with near identical affinity to all five of the muscarinic receptor subtypes as measured by displacement of a muscarinic radioligand, the preponderance of evidence suggests that xanomeline acts preferentially in the ...
Dextran prodrugs are chemically linked drug-polymer complexes in which enzymatic processes and hydrolysis in vivo cause the drug to become pharmacologically active. . Therapeutic agents can be linked to dextran via an ester bond which can be hydrolyzed slowly by esterases to produce sustained, stable dru
Maggot therapy (also known as larval therapy) is a type of biotherapy involving the introduction of live, disinfected maggots (fly larvae) into non-healing skin and soft-tissue wounds of a human or other animal for the purpose of cleaning out the necrotic (dead) tissue within a wound (debridement), and disinfection.
Artificial cells used for drug delivery differ from other artificial cells since their contents are intended to diffuse out of the membrane, or be engulfed and digested by a host target cell. Often used are submicron, lipid membrane artificial cells that may be referred to as nanocapsules, nanoparticles, polymersomes, or other variations of the ...
The letters supposedly detailed the sale of about 150 women for use in experiments for a new soporific (anesthetic) drug. In 2019, this team, curious to see if they could confirm the use of female ...
Sodium polyacrylate can be used for microencapsulation to deliver substances like probiotics. [19] The delivery of probiotics to the digestive system can be difficult because the viability of probiotics decreases sharply throughout the gastrointestinal tract due to strong acid conditions. Although Alginate (Alg) is the most extensively used ...