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Nicotinamide (INN, BAN UK [2]) or niacinamide (USAN US) is a form of vitamin B 3 found in food and used as a dietary supplement and medication. [ 3 ] [ 4 ] [ 5 ] As a supplement, it is used orally (swallowed by mouth) to prevent and treat pellagra (niacin deficiency). [ 4 ]
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Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1]
The bacteria releases a toxin that causes a bright red blotchy rash that has a sandpaper-like texture, and the rash can spread to the entire body and usually first appears on the groin, neck, and ...
The rash appears immediately in irritant contact dermatitis; in allergic contact dermatitis, the rash sometimes does not appear until 24–72 hours after exposure to the allergen. Blisters or wheals: Blisters , wheals (welts), and urticaria (hives) often form in a pattern where skin was directly exposed to the allergen or irritant.
Experts explain how this vitamin B derivative can make a difference for a wide variety of skin concerns and types. Why Niacinamide Is One of the Most In-Demand Ingredients in Skin Care Right Now ...
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The first outbreak of urticaria can lead to other reactions on body parts not directly stimulated, scraped, or scratched. In a normal case, the swelling will decrease without treatment within 15–30 minutes, but, in extreme cases, itchy red welts may last anywhere from a few hours to days.
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