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Some of the symptoms that could possibly occur as a result of a withdrawal from benzodiazepines after long-term use include emotional clouding, [1] flu-like symptoms, [5] suicide, [11] nausea, headaches, dizziness, irritability, lethargy, sleep problems, memory impairment, personality changes, aggression, depression, social deterioration as ...
One of the recommended benzodiazepine taper is to reduce the dose by 50% in the first 4 weeks, maintain the dose for 1–2 months, and then reduce the dose by 25% every 2 weeks. [15] Other common side effects of benzodiazepines are drowsiness, dizziness, somnolence and increased risk of ataxia.
Benzodiazepines are depressants that enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA A receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties.
Benzodiazepine Side Effects. Benzodiazepines can cause side effects, including some that may affect your alertness, physical health and daily life. ... They can also help to promote sleep — a ...
Some prescription drugs like benzodiazepines or tricyclic antidepressants can interfere with the REM stage. ... and certain medications can affect your ability to get enough REM sleep.
Like zaleplon, zolpidem may increase slow-wave sleep but cause no effect on stage 2 sleep. [ 59 ] A 2004 meta-analysis compared benzodiazepines against nonbenzodiazepines and showed few consistent differences between zolpidem and benzodiazepines in terms of sleep onset latency , total sleep duration, number of awakenings, quality of sleep ...
Loprazolam is a short-acting benzodiazepine and is sometimes used in patients who have difficulty in maintaining sleep or have difficulty falling asleep. Hypnotics should only be used on a short-term basis or in those with chronic insomnia on an occasional basis.
Nitrazepam is reported to significantly affect stages of sleep - a decrease in stage 1, 3, and 4 sleep and an increase in stage 2. [83] In young volunteers, the pharmacological properties of nitrazepam were found to produce sedation and impaired psychomotor performance and standing steadiness.