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PRL-8-53 is a nootropic substituted phenethylamine that has been shown to act as a hypermnesic drug in humans; it was first synthesized by medical chemistry professor Nikolaus Hansl at Creighton University in the 1970s as part of his work on amino ethyl meta benzoic acid esters.
Moreover, 3-hydroxymethyl-beta-carboline blocks the sleep-promoting effect of flurazepam in rodents and – by itself – can decrease sleep in a dose-dependent manner. [16] Another derivative, methyl-β-carboline-3-carboxylate, stimulates learning and memory at low doses but can promote anxiety and convulsions at high doses. [15]
3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid is used in the manufacture of six commercial fungicides which are inhibitors of succinate dehydrogenase. [20] [21] Pyrazole is an inhibitor of the alcohol dehydrogenase enzyme, and, as such, is used as an adjuvant with ethanol, to induce alcohol dependency in experimental laboratory mice ...
Most proteins and peptides contain both alcohols and amino groups. Two amino acids are alkanolamines, formally speaking: serine and hydroxyproline. Veratridine and veratrine; Tropane alkaloids such as atropine; hormones and neurotransmitters epinephrine (adrenaline) and norepinephrine (noradrenaline)
Indoxacarb is the active ingredient in a number of household insecticides, including cockroach and ant baits, and can remain active after digestion. [10] In 2012 DuPont's Professional Products including the line of Advion and Arilon products was purchased by Syngenta. [11]
Usually aminomethyl groups feature tertiary amines. Often they are obtained by alkylation with Eschenmoser's salt, a source of [CH 2 =N(CH 3) 2] +. A cobalt(III) complex of aminomethyl is known in the form [Co 2 (CH 2 NH 2)](ClO4) 2. [1] Aminomethyl is the first member of a series of 1-aminoalkyl groups of the form −(CH 2 −) n NH 2. [2]
SR9009, also known as Stenabolic, is a research drug that was developed by professor Thomas Burris of the Scripps Research Institute as an agonist of Rev-ErbA (i.e., increases the constitutive repression of genes regulated by Rev-ErbA) [1] with a half-maximum inhibitory concentration (IC 50) = 670 nM for Rev-ErbAα and IC 50 = 800 nM for Rev-ErbAβ. [2]
2-Amino-5-chloro-4-pentenoic acid, found in the mushroom Amanita cokeri; 2-Methyl-3-pentenoic acid. Some esters are berry fruit flavors. [18] 2-Propyl-trans-2-pentenoic acid (2-en-valproic acid), major metabolite of anticonvulsant valproic acid. [19] cis-2-methyl-2-pentenoic acid 2-methyl-(2Z)-pent-2-enoic acid. (CAS 1617-37-4, FDA 07B8HQZ433 ...